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Registration closed July 15.

BCC2020 is online, global, and affordable. The meeting and training are now done, and the CoFest is under way.

The 2020 Bioinformatics Community Conference brings together the Bioinformatics Open Source Conference (BOSC) and the Galaxy Community Conference into a single event featuring training, a meeting, and a CollaborationFest. Events run from July 17 through July 25, and is held in both the eastern and western hemispheres.

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Sunday, July 19 • 12:05 - 12:10
SigBio-Shiny: A standalone interactive application for detecting biological significance on a set of genes 🍐

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→ Abstract


The presenter(s) will be available for live Q&A in this session (BCC East).

Sangram Keshari Sahu

Independent Researcher, Banglore, India.

Email: sangramsahu15@gmail.com
Project Website: https://github.com/sk-sahu/sig-bio-shiny
Source Code: https://github.com/sk-sahu/sig-bio-shiny
Licence: MIT Licence

Detecting biological significance is an essential step for any high-throughput sequence analysis.
Once sequence reads are mapped and assembled, this is followed by different quantification
analysis which ends up with a set of features (transcript/gene). Quickly exploring those features
together from different angles along with statistical inference gives a good idea about the
biology they are involved.
Doing these kinds of exploration for a particular organism requires an up to date annotation
database. Currently available online/API platforms support either very few or only model
organisms. Apart from that, reproducibility is a primary issue as databases continually updated.
To tackle these problems I am presenting SigBio-Shiny, a standalone interactive application
based on R-Shiny which supports more than just model organisms with no requirement of
manual database maintenance. It leverages available open-source resources such as
Bioconductor's AnnotationHub to col ect the organism's updated database in real-time with
keeping track of what version of the database used. On top of this database, it helps with
detecting biological significance on a set of genes by doing gene mapping, enrichment analysis
of Gene Ontology (GO) and Pathway analysis.
Keywords: Interactive application, Significant biology, Non-model Organism, Annotation
database, Gene mapping, Gene Ontology (GO), Pathway, Enrichment analysis

Speakers
avatar for Sangram Keshari Sahu

Sangram Keshari Sahu

Genomics Data Scientist



Sunday July 19, 2020 12:05 - 12:10 EDT
BOSC
  Meeting-West